Kies de Nederlandse taal
Course module: 202200277
Neurale systeem en onderzoek
Course info
Course module202200277
Credits (ECTS)15
Course typeStudy Unit
Language of instructionDutch
Contact J. le Feber
PreviousNext 5
Examiner L. Alic
B.J. Bergink - Voorthuis
Examiner W.M. Brink
dr. A. van Cappellen van Walsum
Contactperson for the course J. le Feber
Academic year2022
Starting block
Application procedureYou apply via OSIRIS Student
Registration using OSIRISYes
The student is able to 
•    Describe basic anatomic structures of the neural system
•    Describe basic physiological mechanisms of the neural system
•    Perform basic electroencephalogram (EEG) analyses
•    Perform calculations on simple electro-magnetic (EM) fields
•    Explain how (groups of) neurons generate EM fields
•    Describe the physical principles behind NMR and MRI (nuclear spin detection)
•    Critically judge the design and results of published research
•    Use appropriate frequency measures to describe a disease
•    Calculate appropriate association measures that fit to a research design
•    Collect data in a structured manner
•    Use descriptive statistics to characterize a data set in SPSS
In this module we will look at 2 cases where patients with (suspected) epilspsy contacted a neurologist. We will focus on diagnosing and treatment from various perspectives: anatomy/MRI; Neurofysiology, epidemiology/ statistics and fysics. How is the problem diagnosed, how specific is a diagnose and how certain? To answer such questions, this module provides basic knowledge of the anatomy and physiology of the neural system  How is the brain structured and how does it function? In addition, several techniques to investigate the neural system are introduced, like EEG, magnetic resonance imaging (MRI), and electromyography (EMG). Active brain cells induce electromagnetic (EM) fields that can be measured. This module therefore covers the basic physics of EM fields, as summarized in Maxwell’s laws. To determine whether observed EEG differences can be applied in diagnostic tools, basic techniques from statistics and epidemiology are introduced for study design, and to analyze the results. Finally, relevant ethical considerations are discussed.
These themes are combined in the project, which focusses on diagnosis and treatment of a patients neurological problem, and will culminate in a poster presentation..

KEYWORDS: Hersenen; neuron; synaps; axon; elektromagnetische velden; EEG; MRI; EMG; onderzoeksopzet; statistisch toetsen.
Module 7
Participating study
Bachelor Technical Medicine
Required materials
Clinical Neuroanatomy, FitzGerald M.J.T., Folan-Curran J., Uitgever: W. B. Saunders, 2015 (8e editie), ISBN 9780702079092 (op kernboekenlijst)
Clinically Oriented Anatomy, Moore K.L. Williams & Wilkins, Baltimore 2013, 7th edition, ISBN: 9781496354044 (op kernboekenlijst)
Essentials of Neurophysiology; Basic Concepts and Clinical Applications for Scientists and Engineers, Michel van Putten, Springer; 1th edition (April 1, 2009), ISBN 9783540698890 (op kernboekenlijst)
Grant’s Atlas of Anatomy, Agur A.M.R., Lee M.J. Lippincott, Williams & Wilkins, Baltimore 2008, 15th edition, ISBN: 9781975138714 (op kernboekenlijst)
Leerboek Epidemiologie, Bouter, L.M., Van Dongen, M.C.J.M., Zielhuis, G.A., Bohn Stafleu van Loghum , Verschijningsjaar: 2016, ISBN 13: 9789036805612, ISBN 10: 9036805619
Physics for Scientists and Engineers with modern Physics, Giancoli D.C. Prentice Hall 2008 (4th edition), ISBN 9781447965282 (op kernboekenlijst)
Recommended materials
Inleiding tot de Medische Statistiek, Van Houwelingen, J.C., Stijnen, Th., Van Strik; tweede druk (of herdruk 2009); ISBN 978-90-6348009-7
Intermediate Physics for Medicine and Biology, Hobbie, R.K and B. Roth. Springer-Verlag New York Inc. | 5e Editie | 2015, "Hardcover ISBN: 978-3-319-12681-4. Softcover ISBN: 978-3-319-30768-8" (op kernboekenlijst)
Medical Physiology; A cellular and Molecular approach, Boron, WF, Boulpaep, E.L. Philadelphia, 3rd edition, 2016, ISBN 9781455743773 (op kernboekenlijst)
Medische Fysica. Van Oosterom A., Oostendorp T.F., Elsevier Gezondheidszorg,Maarssen 2018 (5e edition), ISBN 9789036810852
Instructional modes
Presence dutyYes

Presence dutyYes


Presence dutyYes

Project supervised
Presence dutyYes

Project unsupervised

Self study without assistance

Patient Case

Neuro Anatomy

Test Neuro Physiology

Practical EMG

MRI and Physics

Test Epidemiology



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