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Cursus: 202100080
202100080
3D bioprinting
Cursus informatieRooster
Cursus202100080
Studiepunten (ECTS)5
CursustypeCursus
VoertaalEngels
Contactpersoondr.ir. J. Rouwkema
E-mailj.rouwkema@utwente.nl
Docenten
Docent
dr. J.C.H. Leijten
Contactpersoon van de cursus
dr.ir. J. Rouwkema
Docent
dr.ir. J. Rouwkema
Docent
dr.ir. C.W. Visser
Collegejaar2021
Aanvangsblok
2B
AanmeldingsprocedureZelf aanmelden via OSIRIS Student
Inschrijven via OSIRISJa
Cursusdoelen
After the course, the students will be able to:
  • Reflect on the different classes of bio-inks and the characteristics which a bio-ink should have
  • Analyze the requirements for the successful extrusion of living cells
  • Consider and apply tissue remodeling within the concept of 4D bioprinting
  • Understand the conceptual potentials and limitations of 3D bioprinting
  • Theorize current challenges and potential solutions in 3D bioprinting
  • Design a project plan to address a current limitation in the field

 
Inhoud
As with all areas of additive manufacturing, 3D bioprinting has seen tremendous progress and developments in the last decade. 3D bioprinting combines advanced 3D fabrication techniques with biological systems to create designed tissue constructs, which can be applied for tissue engineering, as 3D in vitro biological models, or for other applications. This course will provide the student with fundamental insights on important aspects of 3D bioprinting, with a particular emphasis on extrusion bioprinting. Topics include bio-ink development, rheology of 3D bioprinting, inclusion of cells and 4D bioprinting, tissue engineering and translation, biohybrid robotics, and ethics.
  • The content that is covered in the course includes:
  • Introduction, different methodologies for 3D biofabrication, from medical imaging to G-code to print, complexity in tissues
  • Current limitations and main challenges in tissue engineering and 3D biofabrication
  • Bio-inks; tissue derived matrices, biomaterial properties design, multiscale functional materials; crosslinking strategies
  • Rheology of bio-inks, printability, embedded printing
  • Inclusion of cells, tissue remodeling, 4D bioprinting
  • Challenge lecture 1: write a 2-page proposal describing a new optimal 3D bioprinting procedure to produce a patterned construct with a complex shape.
  • Tissue engineering, translation, in-clinic and in-vivo printing
  • Biohybrid robotics
  • Lab-grown meat and leather
  • Environmental, economic, and ethical implications of biofabrication
  • Challenge lecture 2: write a 2-page proposal describing a bio-printed product addressing a pressing societal problem using non-mammalian cells

 
Participating study
Master Mechanical Engineering
Participating study
Master Biomedical Engineering
Verplicht materiaal
Course material
https://mitpress.mit.edu/books/biofabrication
Aanbevolen materiaal
Course material
https://www.sciencedirect.com/book/9780128009727/essentials-of-3d-biofabrication-and-translation
Werkvormen
Assessment
AanwezigheidsplichtJa

Assignment

Lecture

Self study without assistance

Toetsen
Paper

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