Close Help Print Course module: 202100080 202100080 3D bioprinting Course info Schedule Course module 202100080 Credits (ECTS) 5 Course type Course Language of instruction English Contact person dr.ir. J. Rouwkema E-mail j.rouwkema@utwente.nl Lecturer(s) Lecturer dr. J.C.H. Leijten Contactperson for the course dr.ir. J. Rouwkema Lecturer dr.ir. J. Rouwkema Lecturer dr.ir. C.W. Visser Academic year 2021 Starting block 2B Application procedure You apply via OSIRIS Student Registration using OSIRIS Yes Aims After the course, the students will be able to: Reflect on the different classes of bio-inks and the characteristics which a bio-ink should have Analyze the requirements for the successful extrusion of living cells Consider and apply tissue remodeling within the concept of 4D bioprinting Understand the conceptual potentials and limitations of 3D bioprinting Theorize current challenges and potential solutions in 3D bioprinting Design a project plan to address a current limitation in the field   Content As with all areas of additive manufacturing, 3D bioprinting has seen tremendous progress and developments in the last decade. 3D bioprinting combines advanced 3D fabrication techniques with biological systems to create designed tissue constructs, which can be applied for tissue engineering, as 3D in vitro biological models, or for other applications. This course will provide the student with fundamental insights on important aspects of 3D bioprinting, with a particular emphasis on extrusion bioprinting. Topics include bio-ink development, rheology of 3D bioprinting, inclusion of cells and 4D bioprinting, tissue engineering and translation, biohybrid robotics, and ethics. The content that is covered in the course includes: Introduction, different methodologies for 3D biofabrication, from medical imaging to G-code to print, complexity in tissues Current limitations and main challenges in tissue engineering and 3D biofabrication Bio-inks; tissue derived matrices, biomaterial properties design, multiscale functional materials; crosslinking strategies Rheology of bio-inks, printability, embedded printing Inclusion of cells, tissue remodeling, 4D bioprinting Challenge lecture 1: write a 2-page proposal describing a new optimal 3D bioprinting procedure to produce a patterned construct with a complex shape. Tissue engineering, translation, in-clinic and in-vivo printing Biohybrid robotics Lab-grown meat and leather Environmental, economic, and ethical implications of biofabrication Challenge lecture 2: write a 2-page proposal describing a bio-printed product addressing a pressing societal problem using non-mammalian cells   Participating study Master Mechanical Engineering Participating study Master Biomedical Engineering Required materials Course material https://mitpress.mit.edu/books/biofabrication Recommended materials Course material https://www.sciencedirect.com/book/9780128009727/essentials-of-3d-biofabrication-and-translation Instructional modes Assessment Presence duty Yes Assignment Lecture Self study without assistance Tests Paper Close Help Print