Kies de Nederlandse taal
Course module: 202001554
Chemistry of the Biological Cell
Course info
Course module202001554
Credits (ECTS)3
Course typeCourse code module component
Language of instructionEnglish
Contact personprof.dr. M.M.A.E. Claessens
prof.dr. M.M.A.E. Claessens
Contactperson for the course
prof.dr. M.M.A.E. Claessens
Academic year2021
Starting block
Application procedure-
Registration using OSIRISYes
After finishing the course the student is able to:
  • Describe the main groups of proteins and explain their structure in the context of primary, secondary and tertiary structure, the student has insight into how these come about, and how these differ between the main groups.
  • Show insight into the conservation of protein structure in evolution
  • Can explain how (fast) proteins fold and describe the role of chaperones in folding
  • Understand protein interactions in the context of thermodynamics (and can calculate the relevant thermodynamic parameters) and molecular structure.
  • Knows and can recognize the role of specificity and affinity in interactions.
  • Explain how  ultrasensitive responses come about  via cooperativity and allostery and can analyze data in this context.
Proteins are the work horses of life, they are responsible for the processes that make life possible. In this course we will discuss how proteins enable the processes of life. We will explore the fundamental principles that allow proteins to function including protein structure and function. We will also discuss how protein structures have evolved (and are still evolving). The function of proteins comes through their interaction with proteins and other molecules. We will investigate how specific targets are recognized and how interactions can result in ultrasensitive responses. Together the topics covered will give you first insights into how proteins control biological processes.

For a larger, 5-EC course that includes this 3-EC course, check out “Biochemistry”, 201900268.
Assumed previous knowledge
Basic knowledge on thermodynamics and molecular structure.
Participating study
Bachelor Chemical Science & Engineering
Participating study
Bachelor Technology and Liberal Arts & Sciences
Required materials
Title: The molecules of life, physical and chemical principles. Authors: J. Kuriyan, B. Konforti, D. Wemmer. Garland Science. The course will be based on: Chapter 4 Protein structure Chapter 5 Protein evolution Chapter 12 and 13 Molecular recognition Chapter 13 Allostery Chapter 18 Protein folding Other parts of the book will be used in the context of these chapters
Recommended materials
Instructional modes
Presence dutyYes


Presence dutyYes

Chemistry of the biological cell

Kies de Nederlandse taal