- Both theoretical and practical preparation (including safety aspects) of an experiment to be performed according to a known procedure. Another important component is planning of the various elements.
- Performing a (bio-)organic experiment independently.
- Analysing/characterising a synthesised compound.
- Processing the results in a report.
The practical consists of three individual assignments aligned with the lecture.|
It involves a condensation reaction (carbonyl compounds), an electrophilic aromatic substitution reaction and an enzymatically catalysed reaction.
Each assignment involves the synthesis and purification of a compound as well as analysis of the structure and purity of the product obtained using one or more of the following techniques: 1H NMR and IR spectroscopy, UV-Vis spectrophotometry and mass spectrometry. Procedures and a brief theoretical background of the synthesis can be found on Blackboard.
The first practical day begins with a brief (fire) safety instruction. More elaborate instructions and general laboratory technology instructions have already been provided in Q1.
Practical work preparations entail studying (understanding) and elaborating the instructions, completing the hazardous substances information chart and requesting chemicals (and glassware). All of this must be discussed in a preliminary meeting with the assistant.
The reporting element comprises the drafting of a report, using a standard form, of two experiments and a report of the second or third experiment. In addition to the theoretical background, the report must pay enough attention to evaluation of the practical work, both in terms of synthesis and analysis.