Kies de Nederlandse taal
Course module: 193740050
Course infoSchedule
Course module193740050
Credits (ECTS)5
Course typeCourse
Language of instructionEnglish
Contact personR. Bansal
R. Bansal
Contactperson for the course
R. Bansal
dr. M.N.A. Bijman
prof.dr. M.M.A.E. Claessens
prof.dr. A. Kocer
Academic year2022
Starting block
Application procedureYou apply via OSIRIS Student
Registration using OSIRISYes
Upon completion of this course, the student can:

1. Describe primary, secondary, tertiary and quaternary structures of protein; properties of the protein folding; and protein purification, identification and characterization methods.
2. Explain the basic principles of enzyme kinetics and catalysis.
3. Explain how information flows from DNA to protein i.e. describe DNA replication, repair and recombination mechanisms; mechanisms behind RNA and protein synthesis and processing including RNA transcription and splicing, and protein translation.
4. Describe mechanisms of transport, the role of different pumps and ion channels, and biochemistry behind the five primary senses (sight, smell, touch, taste and hearing).
5.Understand the difference between innate and adaptive immune system; and describe the concepts behind antigen recognition and presentation.
6. Discuss the general features of molecular motors that covert chemical energy into mechanical energy.
7. Describe the signal transduction circuits (molecular on-off switches) in biological systems.
8. Describe different metabolic pathways with which environmental energy (food) is converted into the cellular energy (ATP), and discuss which pathway is fuel efficient. Describe how different components i.e. fatty acids, glycogen and proteins are metabolized
Biochemistry is the study of the chemistry of life processes. With this course, we aim to unravel with students the chemistry of life. Topics included are: Protein composition and structure, protein purification, identification and characterization methods; enzyme kinetics and catalysis; DNA, RNA and flow of genetic information; DNA replication, repair and recombination; RNA and protein synthesis; membrane channels and pumps; signal transduction pathways; sensory, immune and molecular motor systems; metabolic pathways including glycolysis, gluconeogenesis, citric acid cycle, oxidative phosphorylation, pentose phosphate;  glycogen, fatty acid and protein metabolism.
Assumed previous knowledge
Gewenst: VWO Scheikunde en Biologie
Participating study
Master Chemical Engineering
Participating study
Master Biomedical Engineering
Participating study
Master Nanotechnology
Required materials
Biochemistry; Authors: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Lubert Stryer; English, 2019; Ninth edition; MacMillan International higher education, New York, 2019; Print ISBN: 9781319114657; eText ISBN: 9781319248062 Chapters from the book that will be covered in this course: Chapter 1-4; 8-9; 13-18; 20-23; 29-31; 34-36
Recommended materials
Instructional modes
Presence dutyYes

Presence dutyYes

Test 1

Kies de Nederlandse taal