To obtain understanding of the working principles, the basic elements and most relevant applications of Lab on a Chip.|
The Lab on a Chip course will take the student to the world of miniaturised systems used in various fields of chemistry and life sciences. A "Lab-on-a-Chip" consists of electrical, fluidic, and optical functions integrated in a microsystem, and has applications in (bio)chemical and medical fields. The core of most lab-on-a-chip system is a microfluidic channel structure, through which nanoliter amounts of liquids with dissolved molecules are propelled, separated and reacted by hydraulic, electrokinetic or surface forces. The fluidic structures are machined in materials like fused silica, borofloat glass, or polymers. The course will treat a number of aspects of such microsystems in seven problem-based learning sessions. Groups of 4 students receive the problem on Monday and try to find solutions to the problem during the week, using a.o. the material offered in a reader. They give a presentation of their solution to the other groups and the teachers on Friday, which is followed by a discussion on the subject treated. The problems offered concern the transport of liquid and dissolved molecules in microsystems, aspects of microfabrication, electrochemical and optical detection methods, the manipulation of cells in microfluidic systems and separations in microfluidic systems. The course is aimed at MSc students of Biomedical Engineering, Electrical Engineering, Nanotechnology, Chemical Engineering, Mechanical Engineering or Applied Physics. |
Principles of fluidics and molecular transport at the micro- and nanoscale; Microfabrication; Chip-based systems for cell studies; On-chip detection methods; On-chip separation methods.
Students who already followed the module Lab on a Chip (201500054) in the bachelor phase are not allowed to follow this course, since there is extensive overlap between the two courses.
Written case study (25%)
Presentations of PBL (5%)